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Isolation (2005 film) - Wikipedia, the free encyclopedia Isolation is a 2005 Irish horror film directed and written by Billy O'Brien and produced by Film Four and Lions Gate Film Studios. Isolation Synopsis - Plot Summary - Fandango.com An experiment in bovine genetic modification goes horrifically wrong in writer/director Billy O'Brien 's debut feature, Isolation. The film was released direct to DVD. Isolation Isolation may refer to: Human isolation (disambiguation) Solitude Solitary confinement Isolationism in politics Isolation (health care) Isolation (psychology. Actors: Eva Amurri Martino: Amy Moore · David Harbour: Dr. Actors: Essie Davis: Orla · Sean Harris: Jamie · Marcel Iures: John · Crispin Letts: Doctor · John Lynch: Dan · Ruth Negga: Mary. John Lynch stars as... An experiment in bovine genetic modification goes horrifically wrong in writer/director Billy O'Brien's debut. John Lynch stars as Dan a cattle. Starring John Lynch, Essie Davis, Marcel Iures. ISOLATION - coming from David Moody and Will Wright 2012 Isolation - a independent horror movie from David Moody and Will Wright Isolation (2005) - Movies | Movie Times | Tickets | Movies Now. Lawrence Moore · Robert Wu: Paul. Isolation (2005) - IMDb Director: Billy O'Brien. Isolation (2011) - IMDb Director: Stephen Kay. Isolation (2005) - Movies | Movie Trailers | Reviews - Rotten Tomatoes Review: An experiment in bovine genetic modification goes horrifically wrong in writer/director Billy O'Brien's debut feature, Isolation. Isolation | Trailer and Cast - Yahoo! Movies Farmer Dan Reilly is having a hard time--he's agreed to allow his cattle to be used in an series of tests by bio-tech laboratory, BV Tech to help him dig his way out. . Sloan · Joshua Close: Jake · Gregg Henry: Dr